Levothyroxine Impurity 58 CAS CATO-C4X-167858
| CAS No. | CATO-C4X-167858 |
| Molecular Formula | C21H17I4NO10 |
| Molecular Weight | 950.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Levothyroxine Impurity 58.
Levothyroxine Impurity 58 (CAS CATO-C4X-167858) is a certified pharmaceutical impurity reference standard with the molecular formula C21H17I4NO10 and a molecular weight of 950.98 g/mol.
Based on its molecular formula C21H17I4NO10, Levothyroxine Impurity 58 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 950.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H17I4NO10 |
| Molecular Weight | 950.98 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine Impurity 57 (CAS CATO-C4X-167857)
- Levothyroxine acyl glucuronide (CAS 909880-81-5)
- Levothyroxine phenolic glucuronide (CAS 21462-56-6)
- Levothyroxine Impurity 29（Mixture of Diastereomers） (CAS CATO-C4X-167829)
- Levothyroxine Impurity 50 (CAS CATO-C4X-167850)
- Levothyroxine Impurity 51 (CAS CATO-C4X-167851)
- Levothyroxine (CAS CATO-C4X-167855)
- Levothyroxine Impurity 54 (CAS CATO-C4X-167854)
Recommended Standards
- β-Lipotropin (1-10), porcine (CAS 77875-68-4)
- Micafungin Impurity 9 (CAS CATO-C4X-16959)
- Rebaudioside C (CAS 63550-99-2)
- Chloride ionophore III (CAS 178959-28-9)
- Pomalidomide Impurity 54 (CAS CATO-C4X-135454)
- Afatinib Impurity 1 (CAS 314771-88-5)
- Carbamazepine Impurity 6 (CAS 40421-03-2)
- Benzyl ((1-((S)-2-amino-3-methylbutanoyl)piperidin-2-yl)methyl)(methyl)carbamate (CAS 1354023-76-9)
- 1-(2-Methylphenyl)cyclobutanamine (CAS 1152587-00-2)
- 4-Amino-N-((2-hydroxycyclohexyl)methyl)butanamide hydrochloride (CAS 1591581-40-6)
- 1-(2,2-Dimethoxy-ethoxy)-3-methyl-benzene (CAS 864684-72-0)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
- Methyl 2,4,5-tris(bromomethyl)-3-methoxybenzoate (CAS 2830607-01-5)
- Peptide 433 (CAS CATO-CPTD788433)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com