Nicardipine Impurity 12 CAS CATO-C4X-171012
| CAS No. | CATO-C4X-171012 |
| Molecular Formula | C26H29N3O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 531.99 g/mol gives Nicardipine Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nicardipine Impurity 12 (CAS CATO-C4X-171012) is a certified pharmaceutical impurity reference standard with the molecular formula C26H29N3O7HCl and a molecular weight of 531.99 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Nicardipine Impurity 12 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 531.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nicardipine Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H29N3O7 HCl |
| Molecular Weight | 531.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Nicardipine Standards
- Nicardipine Impurity N11 (CAS 101-06-4)
- Nicardipine Impurity 24 (CAS 102993-38-4)
- Nicardipine Impurity N1 (CAS 10323-98-5)
- Nicardipine Impurity 36 (CAS 115972-93-5)
- (S)-Nicardipine HCl (CAS 118934-78-4)
- Nicardipine EP Impurity A HCl (CAS 1216817-27-4)
- Nicardipine O-Desmethyl (CAS 123973-71-7)
- Nicardipine Impurity 32 (CAS 134957-01-0)
Recommended Standards
- Nitroso Perindopril EP impurity V (CAS CATO-C4X-125259)
- Alfuzosin EP Impurity A (CAS 98902-36-4)
- Propofol Impurity 43 (CAS CATO-C4X-147343)
- Methyl 2-{[2-(4-bromophenyl)-2-oxoethyl]sulfanyl}acetate (CAS 153783-92-7)
- 5-(4-(Benzyloxy)-3-bromophenyl)oxazole (CAS 2364584-78-9)
- Tryptophan Impurity 49 (CAS CATO-C4X-137349)
- 3,10-Dihydroxydecanoic acid (CAS 762-05-0)
- 8-(Dimethylamino)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 5426-47-1)
- 6-Bromo-1,3,3-trimethylindolin-2-one (CAS 1190861-69-8)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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