Indometacin Impurity 57 CAS 3050535-92-4
| CAS No. | 3050535-92-4 |
| Molecular Formula | C7H9N2O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Indometacin Impurity 57 (CAS 3050535-92-4, C7H9N2O4SNa) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Indometacin Impurity 57 (C7H9N2O4SNa) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H9N2O4S Na |
| Molecular Weight | 240.21 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Indometacin Standards
- Indometacin Impurity 17 (CAS 10414-67-2)
- Indometacin EP Impurity H (CAS 1601-18-9)
- Indometacin EP Impurity I (CAS 16401-99-3)
- Indometacin Impurity 28 (CAS 193603-94-0)
- Indometacin EP Impurity B (CAS 2882-15-7)
- Indometacin EP Impurity C (CAS 4018-82-0)
- Indometacin EP Impurity J (CAS 402849-25-6)
- Indometacin EP Impurity G (CAS 402849-26-7)
Recommended Standards
- Mycophenolate Mofetil EP Impurity E (CAS 31858-66-9)
- Metronidazole Impurity 25 (CAS 16156-93-7)
- Rapamycin Impurity 7 (CAS CATO-C4X-17467)
- Tenofovir Alafenamide Impurity 22 (CAS 376633-26-0)
- 2-Amino-4-methylbenzoxazole (CAS 947504-99-6)
- Methyl 2-(2-(methylsulfonamido)thiazol-4-yl)acetate (CAS 919749-95-4)
- 3-(1,1-Difluoroethyl)-5-fluoroaniline (CAS 1529769-54-7)
- (6-Chloropyridin-3-yl)(phenyl)methanol (CAS 80100-47-6)
- 3-O-Acetyl-17-O-tert-butyldimethylsilyl 5,14-Androstadiene-3-ß,17-ß-diol (CAS 61252-31-1)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com