Pemetrexed Impurity 71 CAS CATO-C4X-172671
| CAS No. | CATO-C4X-172671 |
| Molecular Formula | C27H34N6O6 |
| Molecular Weight | 538.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pemetrexed Impurity 71 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pemetrexed Impurity 71 (CAS CATO-C4X-172671) is a certified pharmaceutical impurity reference standard with the molecular formula C27H34N6O6 and a molecular weight of 538.60 g/mol.
Pemetrexed Impurity 71 (C27H34N6O6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pemetrexed Impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H34N6O6 |
| Molecular Weight | 538.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Pemetrexed Standards
- Pemetrexed Impurity (CAS 1265908-61-9)
- Pemetrexed Impurity 25 (CAS CATO-C4X-172625)
- Pemetrexed Impurity 37 (CAS 144051-68-3)
- Pemetrexed Impurity 55 (CAS CATO-C4X-172655)
- Pemetrexed Impurity 57 (CAS CATO-C4X-172657)
- Pemetrexed Impurity 52 (CAS CATO-C4X-172652)
- Pemetrexed Impurity 51 (CAS CATO-C4X-172651)
- Pemetrexed impurity 46 (CAS CATO-C4X-172646)
Recommended Standards
- Dexamethasone impurity 81 (CAS CATO-C4X-116581)
- Pentoxifylline EP Impurity J (CAS 874747-30-5)
- Dexamethasone impurity 80 (CAS CATO-C4X-116580)
- Pentoxifylline impurity 34 (CAS CATO-C4X-172834)
- Metoclopramide EP Impurity A (CAS 5608-13-9)
- Moxonidine impurity 8 (CAS CATO-C4X-27818)
- Dotinurad Impurity 190 (CAS CATO-C4X-2494190)
- 5-(Furan-2-yl)nicotinic acid (CAS 857283-84-2)
- 4-Propylphenyl chloroformate (CAS 374568-22-6)
- 3-Chloro-5-(difluoromethyl)-4-methylpyridin-2-amine (CAS 1806070-48-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid (CAS 224173-51-7)
- 1-Phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbohydrazide (CAS 94692-06-5)
- Prednisolone Impurity 69 (CAS 31311-61-2)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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