Rizatriptan Impurity 21 CAS CATO-C4X-175221
| CAS No. | CATO-C4X-175221 |
| Molecular Formula | C16H22N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 319.84 g/mol gives Rizatriptan Impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Rizatriptan Impurity 21 (CAS CATO-C4X-175221), a pharmacopoeial impurity reference standard (molecular formula C16H22N5Cl, MW 319.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Rizatriptan Impurity 21 (C16H22N5Cl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H22N5 Cl |
| Molecular Weight | 319.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
- Budesonide Impurity 47 (CAS CATO-C4X-138947)
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- 5-Bromo-6-iodo-1H-indole (CAS 1000343-06-5)
- (S)-3-Methyl-2,3-dihydro-1H-inden-1-one (CAS 935-77-3)
- N,N-Diethyl-2,2-dimethyl-3-pyrrolidinamine (CAS 1934928-68-3)
- 1-(2-Morpholinoethyl)thiourea (CAS 122641-10-5)
- 2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}propan-2-amine (CAS 1510409-49-0)
- tert-Butyl 4-(4-chloro-5-methylpyrimidin-2-yl)-2-methylpiperazine-1-carboxylate (CAS 1261232-46-5)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
Why CATO?
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