Rizatriptan Impurity 22 CAS CATO-C4X-175222
| CAS No. | CATO-C4X-175222 |
| Molecular Formula | C28H32N9 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rizatriptan Impurity 22 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rizatriptan Impurity 22 (CAS CATO-C4X-175222, C28H32N9Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rizatriptan Impurity 22 (C28H32N9Cl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rizatriptan Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H32N9 Cl |
| Molecular Weight | 530.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
- Methylergometrine Impurity 6 (CAS CATO-C4X-19486)
- Iopamidol EP Impurity I (CAS CATO-C4X-145010)
- Epinephrine Impurity 85 (CAS CATO-C4X-184985)
- 4-Hydroxy-2-oxo-1-phenyl-N-(o-tolyl)-2,5-dihydro-1H-pyrrole-3-carboxamide (CAS 1221504-62-6)
- Jujuboside A (CAS 55466-04-1)
- Formoterol impurity 131 (CAS 2386293-34-9（free base）)
- 7-Fluoroimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1388027-96-0)
- 1-[(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide (CAS 400082-70-4)
- 3-Sulfated Lewis A (CAS 153088-71-2)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com