Trandolapril Impurity 18 CAS CATO-C4X-177018
| CAS No. | CATO-C4X-177018 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H21NO2HCl, Trandolapril Impurity 18 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 295.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Trandolapril Impurity 18 (CAS CATO-C4X-177018), a pharmacopoeial impurity reference standard (molecular formula C16H21NO2HCl, MW 295.81 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trandolapril Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 HCl |
| Molecular Weight | 295.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trandolapril Standards
- Trandolapril EP Impurity A (CAS 118194-41-5)
- Trandolapril acyl-β-D-glucuronide (CAS 1260617-50-2)
- Trandolapril-D5 (CAS 1356847-98-7)
- Trandolapril Impurity 3 (2S,3aR,7aS) (CAS 144540-71-6)
- Trandolapril Related Compound 5 HCl (CAS 145513-93-5 (free base))
- Trandolapril EP Impurity D (CAS 149881-40-3)
- Trandolapril Impurity 15 (CAS 760916-37-8)
- Trandolapril Impurity 10 (CAS 83508-14-9)
Recommended Standards
- Dacomitinib Impurity 41 (CAS CATO-C4X-208641)
- Pitavastatin Impurity 126 (CAS 1422058-51-2(free base))
- Relebactam Impurity 23 (CAS CATO-C4X-214423)
- 3-(Prop-2-yn-1-yl)benzonitrile (CAS 1971106-43-0)
- 2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (CAS 545358-46-1)
- 6-Chloro-5-(difluoromethyl)-4-nitropyridine-3-sulfonamide (CAS 1805376-28-6)
- 2-Methyl-2-(4-methylpiperidin-1-yl)propan-1-amine 3580AF 933724-18-6 C10H22N2 (CAS 933724-18-6)
- 2-Fluoro-5-(2-pyridylcarbamoyl)benzeneboronic acid (CAS 1449132-51-7)
- 2-Amino-3-(2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)propanoic acid (CAS 748715-77-7)
- Immunstimulating Peptide, human (CAS 94773-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com