Trandolapril Impurity 9 HCl CAS CATO-C4X-17709
| CAS No. | CATO-C4X-17709 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Trandolapril Impurity 9 HCl (CAS CATO-C4X-17709), a pharmacopoeial impurity reference standard (molecular formula C16H21NO2HCl, MW 295.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H21NO2HCl, Trandolapril Impurity 9 HCl contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 295.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 HCl |
| Molecular Weight | 295.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trandolapril Standards
- Trandolapril EP Impurity A (CAS 118194-41-5)
- Trandolapril acyl-β-D-glucuronide (CAS 1260617-50-2)
- Trandolapril-D5 (CAS 1356847-98-7)
- Trandolapril Impurity 3 (2S,3aR,7aS) (CAS 144540-71-6)
- Trandolapril Related Compound 5 HCl (CAS 145513-93-5 (free base))
- Trandolapril EP Impurity D (CAS 149881-40-3)
- Trandolapril Impurity 15 (CAS 760916-37-8)
- Trandolapril Impurity 10 (CAS 83508-14-9)
Recommended Standards
- Lapatinib Impurity 44 (CAS CATO-C4X-119144)
- Mivacurium chloride Impurity 74 (CAS CATO-C4X-137574)
- Rimegepant Impurity 121 (CAS CATO-C4X-2487121)
- (2R,4S)-4-fluoropyrrolidine-2-carbonitrile;hydrochloride (CAS 2306247-90-3)
- 5-Bromo-6-(cyclopropylmethoxy)nicotinic acid (CAS 912454-38-7)
- (D-Lys3)-GHRP-6 (CAS 136054-22-3)
- 5-Amino-6-cyano-7-phenylisoxazolo[4,5-b]pyridine-3-carboxamide (CAS 76390-75-5)
- Tadalafil Impurity 37 (CAS 171489-59-1)
- PD-166866 (CAS 192705-79-6)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com