Nor-Verapamil D6 HCl CAS CATO-C4X-177847
| CAS No. | CATO-C4X-177847 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 483.08 g/mol gives Nor-Verapamil D6 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nor-Verapamil D6 HCl (CAS CATO-C4X-177847), molecular formula C26H30D6N2O4HCl and molecular weight 483.08 g/mol, is a CATO reference standard with documented purity and traceability.
Nor-Verapamil D6 HCl (C26H30D6N2O4HCl) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H30D6N2O4 HCl |
| Molecular Weight | 483.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Nor Standards
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil Impurity 38 (CAS 114847-42-6)
- Verapamil D6 HCl (CAS 1185032-80-7)
- Verapamil-d7 Hydrochloride (CAS 1188265-55-5)
- Verapamil EP Impurity G (CAS 120-14-9)
- Verapamil EP Impurity J-D7 HCl (CAS 1216413-74-9)
- Verapamil EP Impurity B HCl (CAS 13078-76-7)
- (S)-(-)-Verapamil-d6 Hydrochloride (CAS 1329611-24-6)
Recommended Standards
- Methyl 3-(6-chloro-2-methylpyridin-3-yl)benzoate (CAS 1820673-37-7)
- N-(4-Cyclopropoxy-6-nitropyridin-2-yl)methanesulfonamide (CAS 1243450-33-0)
- 2-Chloro-6-fluoro-3-formylphenylboronic acid (CAS 1451392-95-2)
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- (R)-2-Methyl-3-(pyrrolidin-2-ylmethoxy)pyridine (CAS 161417-20-5)
- (4-Hydroxyphenyl)triphenylphosphonium (CAS 22883-70-1)
- 3-Nitro-2-(phenylethynyl)pyridine (CAS 947330-58-7)
- 2-(tert-Butoxycarbonyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid hydrochloride (CAS 463961-64-0)
- 5-(2,4-Dimethoxyphenyl)uracil (CAS 1005386-84-4)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
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