Tenofovir Alafenamide Impurity 19 CAS CATO-C4X-179719
| CAS No. | CATO-C4X-179719 |
| Molecular Formula | C20H30N10O5P2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Tenofovir Alafenamide Impurity 19 (CAS CATO-C4X-179719, C20H30N10O5P2C6H15N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir Alafenamide Impurity 19 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 653.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H30N10O5P2 C6H15N |
| Molecular Weight | 653.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 11 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Paricalcitol Impurity 43 (CAS CATO-C4X-138743)
- Cefmetazole Impurity 44 (CAS CATO-C4X-150744)
- Oseltamivir Impurity 80 (CAS 793667-32-0)
- VU 0364739 hydrochloride (CAS 1244640-48-9)
- 3-Amino-N-(4-ethylphenyl)benzofuran-2-carboxamide (CAS 1082387-65-2)
- 1-Chloro-8-hydroxyisoquinoline (CAS 1374651-67-8)
- 2,4-Dichlorobenzyl carbamimidothioate hydrochloride (CAS 131916-62-6)
- ethyl 3-(furan-2-yl)-1-methyl-1H-pyrazole-4-carboxylate (CAS 1245106-77-7)
- 2-(2-Chloro-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244084-86-2)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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