Tenofovir Alafenamide Impurity 36 CAS CATO-C4X-179736
| CAS No. | CATO-C4X-179736 |
| Molecular Formula | C21H28BrN6O5P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 671.44 g/mol gives Tenofovir Alafenamide Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Tenofovir Alafenamide Impurity 36 (CAS CATO-C4X-179736, C21H28BrN6O5PC4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H28BrN6O5PC4H4O4, Tenofovir Alafenamide Impurity 36 contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 671.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tenofovir Alafenamide Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H28BrN6O5P C4H4O4 |
| Molecular Weight | 671.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Orforglipron impurity 65 (CAS CATO-C4X-323465)
- Tedizolid Impurity 21 (CAS 1252686-47-7)
- Pregabalin Impurity 66 (CAS 143420-53-5)
- Methyl 3-oxo-2,3-dihydrobenzofuran-7-carboxylate (CAS 1337851-11-2)
- RO-4582640 (4-(8-Benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid) (CAS 426268-06-6)
- 3-(2-Aminoethoxy)propanoic acid hydrochloride (CAS 127457-77-6)
- (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-(((2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 80321-98-8)
- 1,3-Di-Boc-2-(2-Hydroxyethyl)Guanidine (CAS 215050-11-6)
- 3-[5-(2-methoxyethyl)-1,3,4-oxadiazol-2-yl]benzoic acid (CAS 1283020-63-2)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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