Tenofovir Alafenamide Impurity 49 Fumarate CAS CATO-C4X-179749
| CAS No. | CATO-C4X-179749 |
| Molecular Formula | C17H22N5O4P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 507.44 g/mol gives Tenofovir Alafenamide Impurity 49 Fumarate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Tenofovir Alafenamide Impurity 49 Fumarate (CAS CATO-C4X-179749), a pharmacopoeial impurity reference standard (molecular formula C17H22N5O4PC4H4O4, MW 507.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Tenofovir Alafenamide Impurity 49 Fumarate (C17H22N5O4PC4H4O4) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir Alafenamide Impurity 49 Fumarate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H22N5O4P C4H4O4 |
| Molecular Weight | 507.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Apixaban impurity 01 (CAS 501-58-6)
- Tegoprazan Impurity 121 (CAS CATO-C4X-2297121)
- Crisaborole Impurity 147 (CAS CATO-C4X-202147)
- Mirabegron Impurity 107 HCl (CAS CATO-C4X-1032107)
- N-Fmoc-S-(4-methylbenzyl)-L-cysteine (CAS 136050-67-4)
- 4-Bromoisophthalic acid (CAS 6939-93-1)
- 2-((4-Methyl-6-phenylpyridazin-3-yl)oxy)ethanamine (CAS 801203-46-3)
- 5-Bromo-2-butoxy-3-chloropyridine (CAS 1289132-70-2)
- Methyl(([1-(2,2,2-trifluoroethyl)-1h-pyrazol-3-yl]methyl))amine (CAS 1345510-65-7)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com