Tenofovir Alafenamide Impurity 6 CAS CATO-C4X-17976
| CAS No. | CATO-C4X-17976 |
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Tenofovir Alafenamide Impurity 6 (CAS CATO-C4X-17976), a pharmacopoeial impurity reference standard (molecular formula C21H29N6O5PC4H4O4, MW 592.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir Alafenamide Impurity 6 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 592.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H29N6O5P C4H4O4 |
| Molecular Weight | 592.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Brivaracetam Impurity 3 (CAS 357336-99-3)
- Opicapone impurity 28 (CAS CATO-C4X-240428)
- Doxazosin Impurity 10 (CAS 3663-79-4)
- CAS 60701-97-5 (CAS 60701-97-5)
- N-Cyclopropylthiourea (CAS 56541-14-1)
- (2-Fluoro-5-methylphenyl)methanamine (CAS 93071-82-0)
- 6-Fluoro-5-methyl-2,3-dihydro-1H-inden-1-one (CAS 1092347-20-0)
- N-nitroso-folic acid (CAS CATO-C4X-139569)
- Iprovalicarb (CAS 140923-17-7)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com