Theophylline impurity 7 CAS CATO-C4X-18237
| CAS No. | CATO-C4X-18237 |
| Molecular Formula | C7H9N5O4 |
| Molecular Weight | 227.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 227.18 g/mol gives Theophylline impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Theophylline impurity 7 (CAS CATO-C4X-18237, C7H9N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Theophylline impurity 7 (C7H9N5O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9N5O4 |
| Molecular Weight | 227.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Theophylline Standards
- Theophylline Impurity 11 (CAS CATO-C4X-182311)
- Theophylline Impurity 24 (CAS 54965-57-0)
- Theophylline Impurity 18 (CAS 2530-99-6)
- Theophylline Impurity 16 (CAS CATO-C4X-182316)
- Theophylline Impurity 15 (CAS CATO-C4X-182315)
- Theophylline Impurity 10 (CAS CATO-C4X-182310)
- Theophylline Impurity 4 (CAS CATO-C4X-18234)
- Theophylline impurity 6 (CAS CATO-C4X-18236)
Recommended Standards
- 4-nitro-1-nitroso-3-propyl-1H-pyrazole-5-carboxamide (CAS CATO-C4X-249324)
- Tert-butyl (2,2,2-trifluoroacetyl)glycinate (CAS 63959-88-6)
- Boceprevir Impurity 21 (CAS 1568066-82-9)
- n-Isobutyl-n-(2,2,2-trifluoroacetyl)glycine (CAS 344783-88-6)
- Cefmetazole Impurity 38 (CAS CATO-C4X-150738)
- Orforglipron impurity 121 (CAS 2212021-39-9)
- (1R,3r,5S)-Ipratropium Impurity 41 (CAS CATO-C4X-166541)
- 2,7-Bis[(4-methyl-1-piperidinyl)sulfonyl]-9H-fluoren-9-one Oxime (CAS 327061-16-5)
- Ethyl 2-(perfluorophenoxy)acetate (CAS 14742-37-1)
- trans-4-(1,4-Diazepan-1-yl)tetrahydrofuran-3-ol dihydrochloride (CAS 1609403-33-9)
- [4-methyl-2-(3-methylbutoxy)phenyl]methanamine (CAS 1249299-60-2)
- (1R,5S)-1-(3-fluorophenyl)-3-azabicyclo[3.1.0]Hexane (CAS 1932090-09-9)
- 7-Hydroxyquinazoline-2,4(1H,3H)-dione (CAS 861546-03-4)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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