Hydroxychloroquine impurity 64 CAS CATO-C4X-183564
| CAS No. | CATO-C4X-183564 |
| Molecular Formula | C20H30ClN3O |
| Molecular Weight | 363.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Hydroxychloroquine impurity 64.
CATO supplies Hydroxychloroquine impurity 64 (CAS CATO-C4X-183564), a pharmacopoeial impurity reference standard (molecular formula C20H30ClN3O, MW 363.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Hydroxychloroquine impurity 64 (C20H30ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydroxychloroquine impurity 64 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H30ClN3O |
| Molecular Weight | 363.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine impurity 65 (CAS CATO-C4X-183565)
- Hydroxychloroquine Impurity 22 (CAS CATO-C4X-183522)
- Hydroxychloroquine Impurity 89 (CAS CATO-C4X-183589)
- Hydroxychloroquine EP Impurity A (CAS 1449223-88-4)
- Hydroxychloroquine impurity 81 (CAS CATO-C4X-183581)
- Hydroxychloroquine Impurity 91 (CAS CATO-C4X-183591)
- Hydroxychloroquine Impurity 31 (CAS CATO-C4X-183531)
- Hydroxychloroquine Impurity 7 (CAS 47493-14-1)
Recommended Standards
- 7-Bromo-2,4-dichloro-8-fluoro-6-(trifluoromethyl)quinazoline (CAS 2134618-53-2)
- 4-Chloro-N-(6-(methylthio)benzo[d]thiazol-2-yl)benzo[d]thiazol-2-amine (CAS 890940-19-9)
- (4-Bromo-3-(difluoromethyl)-5-iodopyridin-2-yl)methanol (CAS 1804670-88-9)
- Buthiazide-d10 (Major) (CAS 1330189-19-9)
- Famotidine EP Impurity B (CAS 89268-62-2（free base)）)
- Albendazole Impurity N78 (CAS 139751-05-6)
- Letrozole Impurity 12 (CAS CATO-C4X-182912)
- 3-Bromo-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)nitrobenzene (CAS 1774894-60-8)
- 3-(3-Chlorophenoxy)azetidine (CAS 868833-95-8)
- 3-Bromo-4-fluoro-N-methoxy-N-methylbenzamide (CAS 1220124-55-9)
- Chroman-5-carbaldehyde (CAS 209256-63-3)
- Ethyl furo[3,2-c]pyridine-2-carboxylate (CAS 138173-84-9)
- 2-(Benzofuro[3,2-d]pyrimidin-4-ylthio)acetamide (CAS 847337-32-0)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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