Clemastine Impurity 16 CAS CATO-C4X-183716
| CAS No. | CATO-C4X-183716 |
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Clemastine Impurity 16 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Clemastine Impurity 16 (CAS CATO-C4X-183716) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26ClNO and a molecular weight of 343.89 g/mol.
Clemastine Impurity 16 (C21H26ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clemastine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clemastine Standards
- rac-Clemastine Fumarate EP Impurity B (CAS 61771-18-4)
- Clemastine Impurity 15 (CAS CATO-C4X-183715)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine Impurity 21 (CAS CATO-C4X-183721)
- Clemastine Impurity 22 (CAS CATO-C4X-183722)
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 33 (CAS CATO-C4X-183733)
- Clemastine Impurity 32 (CAS CATO-C4X-183732)
Recommended Standards
- Sertraline Impurity 63 (CAS CATO-C4X-134463)
- Sertraline Impurity 62 (CAS CATO-C4X-134462)
- Sertraline Impurity 61 (CAS CATO-C4X-134461)
- Sertraline Impurity 60 (CAS CATO-C4X-134460)
- Galantamine EP Impurity B (CAS 1668-85-5)
- Vitamin K1 Impurity 71 (CAS 2457204-51-0)
- Vigabatrin EP Impurity E (CAS 1378466-25-1)
- 5-Phenylpent-1-yn-3-ol (CAS 67648-04-8)
- 4-Amino-2-chloro-5-pyrimidinecarbonitrile (CAS 94741-69-2)
- 5-Ethoxypyrazine-2-carbonyl chloride (CAS 58333-67-8)
- 4-((5-Bromothiophen-2-yl)sulfonyl)-7-phenyl-1,4-thiazepane (CAS 1797347-94-4)
- tert-Butyl 2-(2,2-dibromovinyl)pyrrolidine-1-carboxylate (CAS 316141-29-4)
- 5,5-dimethylpyrrolidin-3-one hydrochloride (CAS 1247867-80-6)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com