Clemastine Impurity 24 CAS CATO-C4X-183724
| CAS No. | CATO-C4X-183724 |
| Molecular Formula | C20H23ClN2O2 |
| Molecular Weight | 358.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H23ClN2O2, Clemastine Impurity 24 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 358.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Clemastine Impurity 24 (CAS CATO-C4X-183724, C20H23ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clemastine Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O2 |
| Molecular Weight | 358.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clemastine Standards
- Clemastine Impurity 14 (CAS CATO-C4X-183714)
- Clemastine EP Impurity A(Mixture of Diastereomers) (CAS 108825-05-4)
- Clemastine Impurity 33 (CAS CATO-C4X-183733)
- rac-Clemastine Fumarate EP Impurity B (CAS 61771-18-4)
- Clemastine Impurity 15 (CAS CATO-C4X-183715)
- Clemastine Impurity 16 (CAS CATO-C4X-183716)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine Impurity 21 (CAS CATO-C4X-183721)
Recommended Standards
- Clotrimazole Impurity 24 (CAS 98751-53-2)
- Carbophenothion-sulfoxide (CAS 17297-40-4)
- Clotrimazole Impurity 23 (CAS 289887-34-9)
- 2-Amino-4-((4-chlorobenzyl)thio)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile (CAS 478067-10-6)
- Isoniazid EP Impurity D (CAS 553-53-7)
- Finerenone Impurity 131 (CAS CATO-C4X-2880131)
- Lotilaner Impurity 2 (CAS CATO-C4X-32562)
- 1,7-Dioxacycloheptadecan-8-one (CAS 3391-83-1)
- 2-Ethylpiperazine dihydrochloride (CAS 438050-52-3)
- n-(2-Aminoethyl)-1,5-dimethyl-1h-pyrazole-3-carboxamide (CAS 1001519-26-1)
- (4R,4′R)-2,2′-(1H-Pyrazole-3,5-diyl)bis[4,5-dihydro-4-phenyloxazole] (CAS 1207950-69-3)
- Caroverine (CAS 23465-76-1)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-84-0)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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