Daclatasvir Impurity 2 CAS CATO-C4X-18482
| CAS No. | CATO-C4X-18482 |
| Molecular Formula | C18H17BrO2 |
| Molecular Weight | 345.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Daclatasvir Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Daclatasvir Impurity 2 (CAS CATO-C4X-18482, C18H17BrO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Daclatasvir Impurity 2 (C18H17BrO2) is characterized by a steroid core, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H17BrO2 |
| Molecular Weight | 345.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Daclatasvir Standards
- Daclatasvir Impurity 34 (CAS CATO-C4X-184834)
- Daclatasvir Impurity 17 (CAS CATO-C4X-184817)
- Daclatasvir Impurity 10 (CAS CATO-C4X-184810)
- Daclatasvir Impurity 1 (CAS 36934-45-9)
- Daclatasvir impurity 38 (CAS CATO-C4X-184838)
- Daclatasvir impurity 39 (CAS CATO-C4X-184839)
- Daclatasvir EP Impurity H (CAS 1007882-27-0)
- Daclatasvir Impurity 9 (CAS CATO-C4X-18489)
Recommended Standards
- Varenicline Metadinitro (CAS 853946-18-6)
- Varenicline Impurity 20 (CAS 230615-59-5)
- Varenicline Nitroso Impurity 4 (CAS CATO-C1911208)
- Pretomanid Impurity 9 (CAS CATO-C4X-26069)
- Betaxolol EP Impurity C (CAS 63659-17-6)
- Chlorphenamine Impurity 26 (CAS CATO-C4X-118826)
- Caffeine Impurity 11 (CAS 85438-96-6)
- Poly(4-styrenesulfonic acid) lithium salt (CAS 9016-91-5)
- 2-(Tetrahydro-2H-thiopyran-4-yl)thiazole-4-carboxamide (CAS 1936315-97-7)
- Bortezomib Impurity 40 (CAS 87304-47-0)
- Methyl 2-(difluoromethyl)-5-fluorobenzoate (CAS 2260732-59-8)
- 3-(3-Chlorobenzoyl)-4-methylpyridine (CAS 158978-30-4)
- Tert-butyl (4-acetylcyclohexyl)carbamate (CAS 1374656-14-0)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com