Hydrocortisone Impurity 01 CAS 10215-75-5
| CAS No. | 10215-75-5 |
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Hydrocortisone Impurity 01 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Hydrocortisone Impurity 01 (CAS 10215-75-5) is a certified pharmaceutical impurity reference standard with the molecular formula C25H32O8 and a molecular weight of 460.52 g/mol.
The molecular framework of Hydrocortisone Impurity 01 (C25H32O8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H32O8 |
| Molecular Weight | 460.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Hydrocortisone Standards
- Hydrocortisone impurity 40 (CAS 33767-18-9)
- Hydrocortisone Impurity 60 (CAS CATO-C4X-140160)
- Hydrocortisone Impurity 61 (CAS CATO-C4X-140161)
- Hydrocortisone 17-Propionate 21-Acetate (CAS 74050-20-7)
- Hydrocortisone Impurity 39 (CAS 3593-96-2)
- Hydrocortisone Impurity 32 (CAS 103242-89-3)
- Hydrocortisone Impurity 67 (CAS 146201-55-0)
- Hydrocortisone Impurity 75 (CAS 220489-73-6)
Recommended Standards
- 3,8-Bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-1,10-phenanthroline (CAS 1001330-07-9)
- 1-(Benzofuro[3,2-d]pyrimidin-4-yl)-N-(3,4-dimethoxyphenethyl)piperidine-4-carboxamide (CAS 1112292-68-8)
- N-(4-(5-(Benzo[d][1,3]dioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide (CAS 853625-60-2)
- 3,5-Dihydroxy-2-isobutyryl-4,4-dimethyl-6-(2,4,6-trihydroxy-3-methyl-5-(2-methylbutanoyl)benzyl)cyclohexa-2,5-dien-1-one (CAS 112663-68-0)
- Thiotepa Impurity 1 (CAS 90877-51-3)
- Goserelin EP Impurity D Acetate (CAS CATO-C4X-19204)
- Omeprazole Impurity 11 (CAS CATO-C4X-125511)
- 4-((Chloromethyl)sulfonyl)morpholine (CAS 39542-27-3)
- Naphthalene-1-sulfinic acid (CAS 607-33-0)
- Fenfuram Impurity 14 (CAS 28562-71-2)
- 1-(Benzenesulfonyl)-3-[(3-chlorophenyl)sulfanyl]propan-2-ol (CAS 338409-59-9)
- 1-(2,4,6-Triisopropylphenyl)ethan-1-one (CAS 2234-14-2)
- (2,6-Dimethylmorpholino)(3-(trifluoromethyl)phenyl)methanone (CAS 866150-15-4)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com