Nicorandil Impurity 23 HCl CAS CATO-C4X-190723
| CAS No. | CATO-C4X-190723 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Nicorandil Impurity 23 HCl (CAS CATO-C4X-190723), a pharmacopoeial impurity reference standard (molecular formula C8H10N2O2HCl, MW 202.64 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nicorandil Impurity 23 HCl (C8H10N2O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Nicorandil Impurity 23 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 HCl |
| Molecular Weight | 202.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Nicorandil Standards
- Nicorandil N-Oxide (CAS 107833-98-7)
- Nicorandil-d4 (CAS 1132681-23-2)
- Nicorandil Impurity 7 (CAS 113743-17-2)
- Nicorandil Impurity 5 (CAS 1157-74-0)
- Nicorandil Impurity 47 (CAS 13362-26-0)
- Nicorandil Impurity 26 (CAS 14906-63-9)
- Nicorandil Impurity 24 (CAS 149415-43-0)
- Nicorandil Impurity 43 (CAS 1570-45-2)
Recommended Standards
- Dapoxetine Impurity 89 (CAS CATO-C4X-143989)
- Febuxostat Impurity 61 (CAS 2418591-42-9)
- Buspirone Impurity 22 (CAS 223461-35-6)
- 7’’-O-Methylsciadopitysin (CAS 3778-25-4)
- 5-Bromo-6-(trifluoromethyl)pyrimidin-4-amine (CAS 1260844-01-6)
- tert-Butyl methyl(1-((pyridin-3-yloxy)methyl)cyclopropyl)carbamate (CAS 387845-55-8)
- N-methyl-N-(6-methylpicolinoyl)glycine (CAS 953901-06-9)
- 2-Chloro-6-(4-(2-chloro-4-nitrophenyl)buta-1,3-dien-1-yl)benzene-1-sulfonyl fluoride (CAS 31368-31-7)
- 3-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-amine (CAS 1352398-22-1)
- Neuropeptide S (human) (CAS 412938-67-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com