Rotigotine EP Impurity I HCl CAS CATO-C4X-192710
| CAS No. | CATO-C4X-192710 |
| Molecular Formula | C26H31NO3S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rotigotine EP Impurity I HCl (CAS CATO-C4X-192710) is a certified pharmaceutical impurity reference standard with the molecular formula C26H31NO3S2HCl and a molecular weight of 506.12 g/mol.
The molecular framework of Rotigotine EP Impurity I HCl (C26H31NO3S2HCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rotigotine EP Impurity I HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H31NO3S2 HCl |
| Molecular Weight | 506.12 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Rotigotine Standards
- Rotigotine Impurity 11 (CAS 101403-24-1)
- Rotigotine impurity 23 (CAS 101470-23-9)
- Rotigotine EP Impurity B Hydrochloride (CAS 101470-23-9（free base）)
- Rotigotine Racemate HCl (CAS 102120-99-0)
- Rotigotine Impurity 40 (CAS 102121-00-6)
- Rotigotine EP Impurity A (CAS 112835-48-0)
- Rotigotine EP Impurity A HCl (CAS 112835-48-0（free base）)
- Rotigotine EP Impurity H (CAS 1148154-91-9)
Recommended Standards
- Ritonavir Impurity 1 (CAS 201409-23-6)
- Tolterodine EP Impurity E (CAS 480432-14-2)
- Posaconazole Impurity 166 (CAS 1631169-28-2)
- Methyl 5-(4-methylphenyl)isoxazole-3-carboxylate (CAS 517870-14-3)
- 2,5-Di-p-tolyl-1,3,4-oxadiazole (CAS 2491-91-0)
- 2-Ethylhexyl 2-chloropropanoate (CAS 92705-03-8)
- Ambroxol impurity 108 (CAS 73220-00-5)
- 2-(Chloromethyl)-3-(difluoromethyl)-6-iodopyridine-4-carboxylic acid (CAS 1805261-57-7)
- 1-(4-Chlorophenyl)-N-(2-ethoxyphenyl)-6-methyl-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 869875-89-8)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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