Doxycycline EP Impurity C（HCl） CAS CATO-C4X-193114
| CAS No. | CATO-C4X-193114 |
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Doxycycline EP Impurity C（HCl） (CAS CATO-C4X-193114, C22H24N2O8HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Doxycycline EP Impurity C（HCl） (C22H24N2O8HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Doxycycline EP Impurity C（HCl） under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O8 HCl |
| Molecular Weight | 480.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Doxycycline Standards
- Doxycycline Hydrochloride (CAS 10592-13-9)
- Doxycycline EP Impurity F (CAS 122861-53-4)
- Doxycycline Monohydrate (CAS 17086-28-1)
- Doxycycline-13CD3 (CAS 1902958-13-7)
- Doxycycline Impurity 20 (CAS 2000233-92-9)
- Doxycycline Hyclate (CAS 24390-14-5)
- Doxycycline-d3 (CAS 2747918-45-0)
- Doxycycline-d3 HCl (CAS 2747918-45-0 (free base))
Recommended Standards
- Fudosteine Impurity 23 HCl (CAS CATO-C4X-144723)
- Urapidil Impurity 85 (CAS 144965-19-5 (free base))
- Famotidine EP Impurity A (CAS 124646-10-2)
- 3-Methoxy-5,6-dimethylpyrazin-2-ol (CAS 100868-74-4)
- 3,6-Dichloro-2-iodobenzaldehyde (CAS 861081-48-3)
- 2-(2-Chlorophenyl)-4-(pyren-1-ylmethylene)oxazol-5(4H)-one (CAS 71977-19-0)
- 1-(4-Bromophenyl)ethan-1-amine hydrochloride (CAS 90006-14-7)
- 1-Butyl-2-methyl-4-nitro-1H-imidazole (CAS 135009-57-3)
- 4-Cyclopropoxy-N,N-dimethyl-5-(methylamino)picolinamide (CAS 1243286-61-4)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com