Doxycycline Hyclate EP Impurity F CAS CATO-C4X-19319
| CAS No. | CATO-C4X-19319 |
| Molecular Formula | C23H25NO8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Doxycycline Hyclate EP Impurity F (CAS CATO-C4X-19319), a pharmacopoeial impurity reference standard (molecular formula C23H25NO8HCl, MW 479.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Doxycycline Hyclate EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 479.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H25NO8 HCl |
| Molecular Weight | 479.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Doxycycline Standards
- Doxycycline Hydrochloride (CAS 10592-13-9)
- Doxycycline EP Impurity F (CAS 122861-53-4)
- Doxycycline Monohydrate (CAS 17086-28-1)
- Doxycycline-13CD3 (CAS 1902958-13-7)
- Doxycycline Impurity 20 (CAS 2000233-92-9)
- Doxycycline Hyclate (CAS 24390-14-5)
- Doxycycline-d3 (CAS 2747918-45-0)
- Doxycycline-d3 HCl (CAS 2747918-45-0 (free base))
Recommended Standards
- Cefixime Impurity 80 (CAS CATO-C4X-113980)
- Omeprazole Impurity 25 (CAS 73590-93-9)
- Teneligliptin impurity 56 TFA (CAS 2407632-31-7（free base）)
- 2-Fluoro-5-iodo-3-methylpyridine (CAS 205245-17-6)
- Ethyl 2-(((tert-butoxycarbonyl)amino)methyl)-6-fluorospiro[3.3]heptane-2-carboxylate (CAS 2715119-98-3)
- Venetoclax Impurity 156 (CAS 4350-73-6)
- (1,3-Dioxolan-2-yl)-acetic acid butyl ester (CAS 1263366-16-0)
- (S)-2-((1-Acetylpiperidin-3-yl)oxy)acetic acid (CAS 1354019-56-9)
- 4-[5-(2,4-Dichlorophenyl)-1H-pyrazol-3-yl]-1-(2-nitrobenzenesulfonyl)piperidine (CAS 1031236-58-4)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com