Tolvaptan Impurity 70 CAS CATO-C4X-195570
| CAS No. | CATO-C4X-195570 |
| Molecular Formula | C18H17ClN2O3 |
| Molecular Weight | 344.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tolvaptan Impurity 70 (CAS CATO-C4X-195570, C18H17ClN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H17ClN2O3, Tolvaptan Impurity 70 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 344.79 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity 70 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN2O3 |
| Molecular Weight | 344.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan impurity 113 (CAS CATO-C4X-1955113)
- Tolvaptan Impurity 1 (CAS 247237-38-3)
- Tolvaptan Impurity 6 (CAS 193686-76-9)
- Tolvaptan Impurity 122 (CAS CATO-C4X-1955122)
- Tolvaptan Impurity 121 (CAS CATO-C4X-1955121)
- Tolvaptan Impurity 120 (CAS CATO-C4X-1955120)
- Tolvaptan Impurity 8 (CAS 1432725-24-0)
- Tolvaptan Impurity 20 (CAS 137982-91-3)
Recommended Standards
- N-(tert-butyl)-7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 343375-46-2)
- Tivozanib Impurity 5 (CAS CATO-C4X-34005)
- Ethyl 2-((6-chloro-2-phenyl-1H-benzo[d]imidazol-1-yl)oxy)propanoate (CAS 282523-39-1)
- 4-Chloro-6-{4-[5-(furan-2-yl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine (CAS 1026080-38-5)
- Dantrolene Impurity 1 (CAS 7147-77-5)
- Roxadustat Impurity 166 (CAS CATO-C4X-2213166)
- Pemafibrate Impurity 82 (CAS CATO-C4X-290382)
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-((benzyloxy)carbonyl)piperidine-4-carboxylic acid (CAS 368866-10-8)
- (1S,3s)-1-((tert-butoxycarbonyl)amino)-3-methoxycyclobutane-1-carboxylic acid (CAS 2166823-89-6)
- methyl 2-{[(propan-2-ylidene)amino]oxy}hexanoate (CAS 5001-41-2)
- 7-(Piperidin-2-yl)-5-(trifluoromethyl)imidazo[1,2-a]pyrimidine dihydrochloride (CAS 1361114-75-1)
- Cloperastine Impurity 2 (CAS 4960-10-5)
- 1-(2-Chloroethoxy)propan-2-ol (CAS 871-57-8)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com