Nebivolol EP Impurity C CAS CATO-C4X-196848
| CAS No. | CATO-C4X-196848 |
| Molecular Formula | 2*C29H31F2NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nebivolol EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Nebivolol EP Impurity C (CAS CATO-C4X-196848, C29H31F2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Nebivolol EP Impurity C (C29H31F2NO4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 495.57 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | 2*C29H31F2NO4 |
| Molecular Weight | 495.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 20 (CAS 105300-40-1)
- Nebivolol Impurity 28 (CAS 112068-01-6)
- D-Nebivolol (SR,RR) (CAS 118457-15-1)
- L-Nebivolol (RS,SS) (CAS 118457-16-2)
- Nebivolol Hydrochloride EP Impurity B (CAS 119365-23-0)
- Nebivolol Impurity 32（SS,RS）or（SR,SS） (CAS 119365-25-2)
Recommended Standards
- Trazodone impurity 54 (CAS CATO-C4X-177254)
- Methylene blue Impurity 16 (CAS CATO-C4X-189616)
- Ezetimibe Impurity 41 (CAS CATO-C4X-109841)
- 2-Methoxythiazolo[5,4-b]pyridine (CAS 67219-27-6)
- 2-((Imidazo[2,1-b]thiazol-6-ylmethyl)thio)benzo[d]oxazole (CAS 300572-38-7)
- 6-Fluoro-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-amine (CAS 2248-44-4)
- Avanafil Impurity 12 (CAS CATO-C4X-111812)
- 2-(Methylthio)-6-(trifluoromethyl)thiazolo[4,5-b]pyridine (CAS 488738-38-1)
- Ethyl 4-(2-bromophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 283593-06-6)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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