Nebivolol Impurity 50 CAS CATO-C4X-196850
| CAS No. | CATO-C4X-196850 |
| Molecular Formula | C20H21FO6S |
| Molecular Weight | 408.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Nebivolol Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Nebivolol Impurity 50 (CAS CATO-C4X-196850, C20H21FO6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H21FO6S, Nebivolol Impurity 50 contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H21FO6S |
| Molecular Weight | 408.44 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 105 (CAS 1345202-53-0)
- rac Nebivolol-d4 (CAS 1219407-55-2)
- Nebivolol Impurity 12（RS,SR） (CAS 119365-30-9)
- Nebivolol Impurity 13（SR,SR） (CAS CATO-C4X-196813)
- Nebivolol Impurity 19 (CAS CATO-C4X-196819)
- Nebivolol Impurity 3（RR,SS） (CAS 1360598-84-0)
- L-Nebivolol (RS,SS) (CAS 118457-16-2)
- Nebivolol Impurity 31（RR,SR）or（RS,RR） (CAS 119365-26-3)
Recommended Standards
- ISPA-28 (CAS 1006335-39-2)
- Xanthone I (CAS 35349-68-9)
- 7-Methoxy-4-(pyridin-3-yl)-6-[2-(quinolin-2-yl)ethoxy]quinazoline (CAS 1006890-01-2)
- Triacetoxyscirpenol (CAS 4297-61-4)
- Phloroglucinol Impurity 68 (CAS CATO-C4X-221768)
- Tedizolid Impurity 42 (CAS 2095200-69-2)
- Sofosbuvir Impurity 9 (CAS 2173637-26-6)
- 1-(3-(3-Methoxyphenyl)propyl)piperazine (CAS 58030-26-5)
- 1-Ethoxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)benzene (CAS 124729-02-8)
- 3-(3,5-Bis(methylsulfonyl)phenyl)propanoic acid (CAS 1040682-15-2)
- Methyl 3-fluoro-5-iodothiophene-2-carboxylate (CAS 2166596-47-8)
- 2-(2,3-Difluorophenyl)pyrrolidine (CAS 1249722-04-0)
- N-(5,7-Dimethylbenzo[d]thiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide (CAS 897618-14-3)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com