Nebivolol Impurity 51（SS+RR+RS+SR） CAS CATO-C4X-196851
| CAS No. | CATO-C4X-196851 |
| Molecular Formula | 4*C19H22FNO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nebivolol Impurity 51（SS+RR+RS+SR） (CAS CATO-C4X-196851), a pharmacopoeial impurity reference standard (molecular formula C19H22FNO2, MW 315.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H22FNO2, Nebivolol Impurity 51（SS+RR+RS+SR） contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 315.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nebivolol Impurity 51（SS+RR+RS+SR） under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 4*C19H22FNO2 |
| Molecular Weight | 315.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 20 (CAS 105300-40-1)
- Nebivolol Impurity 28 (CAS 112068-01-6)
- D-Nebivolol (SR,RR) (CAS 118457-15-1)
- L-Nebivolol (RS,SS) (CAS 118457-16-2)
- Nebivolol Hydrochloride EP Impurity B (CAS 119365-23-0)
- Nebivolol Impurity 32（SS,RS）or（SR,SS） (CAS 119365-25-2)
Recommended Standards
- Argatroban Impurity 73 (CAS CATO-C4X-100773)
- Testosterone Impurity 70 (CAS 15216-04-3)
- Fluoxetine Impurity 43 (CAS CATO-C4X-135243)
- 2-Methoxycyclooctan-1-amine (CAS 953904-44-4)
- 5-Bromo-3-fluorophthalic acid (CAS 344309-11-1)
- 6-formyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid (CAS 15811-14-0)
- Methyl 2-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)acetate (CAS 1648864-47-4)
- 3-Bromo-5-chloro-2-iodopyridine (CAS 823221-97-2)
- Phloroglucinol impurity 58 (CAS 1521-61-5)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com