Nebivolol Impurity 94 CAS CATO-C4X-196894
| CAS No. | CATO-C4X-196894 |
| Molecular Formula | C40H44ClF2N3O8 |
| Molecular Weight | 768.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Nebivolol Impurity 94 (C40H44ClF2N3O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 768.24 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Nebivolol Impurity 94 (CAS CATO-C4X-196894) is a certified pharmaceutical impurity reference standard with the molecular formula C40H44ClF2N3O8 and a molecular weight of 768.24 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nebivolol Impurity 94 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H44ClF2N3O8 |
| Molecular Weight | 768.24 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Nebivolol Standards
- Nebivolol Impurity 93 (CAS CATO-C4X-196893)
- Nebivolol Impurity 95 (CAS CATO-C4X-196895)
- Nebivolol Impurity 98 (CAS CATO-C4X-196898)
- Nebivolol Impurity 90 (CAS CATO-C4X-196890)
- Nebivolol Impurity 92 (CAS CATO-C4X-196892)
- Nebivolol Impurity 101 (CAS CATO-C4X-1968101)
- Nebivolol Impurity 96 (CAS CATO-C4X-196896)
- Nebivolol Impurity 100 (CAS CATO-C4X-1968100)
Recommended Standards
- Ceftazidime impurity 119 (CAS CATO-C4X-1212119)
- Cefdinir Impurity 82 (CAS 2489663-67-2)
- 2,4,6-TRis(m-terphenyl-5'-yl)boroxin (CAS 909407-14-3)
- (2R)-3-(hexadecyloxy)-2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxy}propyl 2-(trimethylazaniumyl)ethyl phosphate 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine 1-O-hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine 86288-11-1 CHEBI:55430 PC(O-16:0/20:4(5Z,8Z,11Z,14Z)) (CAS 86288-11-1)
- Vonoprazan Impurity 240 (CAS CATO-C4X-1020240)
- Cefprozil Impurity 12 (CAS CATO-C4X-149212)
- Adenosine Impurity 10 (CAS 5987-73-5)
- (4-(Methylamino)phenyl)methanol (CAS 181819-75-0)
- Ethyl 3,5-dichloro-2-fluorobenzoate (CAS 1520350-87-1)
- 1-(2-Methoxy-5-methylphenyl)guanidine methanesulfonate (CAS 1426291-43-1)
- methyl 3-(2-hydroxypropan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate (CAS 83249-19-8)
- 2-(3-Amino-4-chloro-1h-pyrazol-1-yl)-n-(2-methoxyethyl)acetamide (CAS 1344066-59-6)
- Clentiazem (CAS 96125-53-0)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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