Nebivolol Impurity 92 CAS CATO-C4X-196892
| CAS No. | CATO-C4X-196892 |
| Molecular Formula | C34H45F2NO14 |
| Molecular Weight | 729.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nebivolol Impurity 92 (C34H45F2NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Nebivolol Impurity 92 (CAS CATO-C4X-196892, C34H45F2NO14) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H45F2NO14 |
| Molecular Weight | 729.72 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 90 (CAS CATO-C4X-196890)
- Nebivolol Impurity 93 (CAS CATO-C4X-196893)
- Nebivolol Impurity 94 (CAS CATO-C4X-196894)
- Nebivolol Impurity 101 (CAS CATO-C4X-1968101)
- Nebivolol Impurity 96 (CAS CATO-C4X-196896)
- Nebivolol Impurity 95 (CAS CATO-C4X-196895)
- Nebivolol Impurity 98 (CAS CATO-C4X-196898)
- Nebivolol Impurity 100 (CAS CATO-C4X-1968100)
Recommended Standards
- Elagolix Impurity 36 (CAS 2409132-64-3)
- Benzyl 2-acetamido-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-a-D-glucopyranoside (CAS 67313-30-8)
- Fibronectin Analog (CAS 125455-58-5)
- Benzyl 2-Acetamido-2-deoxy-4,6-O-benzylidene-3-O-(2,3,4,6-tetra- O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranoside (CAS 86327-84-6)
- Mesna impurity 15 (CAS CATO-C4X-169215)
- Finerenone Impurity 15 (CAS 3046142-41-7)
- Leflunomide Impurity 17 (CAS 67305-24-2)
- Ceritinib Impurity 17 (CAS CATO-C4X-104817)
- 3,6-dihydroxy-2-methyl-3,4-dihydroquinazolin-4-one (CAS 1322604-74-9)
- 2-(4-Ethoxyphenoxy)-5-methylaniline (CAS 946728-53-6)
- Aciclovir Impurity 33 (CAS CATO-C4X-101033)
- 3-Ethylamino-pyrrolidine-1-carboxylic acid benzyl ester (CAS 1354020-82-8)
- Sulfaethylthiadiazole (CAS 94-19-9)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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