Doxapram Impurity 14 CAS CATO-C4X-197314
| CAS No. | CATO-C4X-197314 |
| Molecular Formula | C18H18INO |
| Molecular Weight | 391.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Doxapram Impurity 14 (C18H18INO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Doxapram Impurity 14 (CAS CATO-C4X-197314, C18H18INO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Doxapram Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18INO |
| Molecular Weight | 391.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Doxapram Standards
- Doxapram Impurity 1 (2-Ketodoxapram) (CAS 42595-88-0)
- Doxapram N-Oxide (CAS CATO-C4X-197312)
- Doxapram Impurity 22 (CAS CATO-C4X-197322)
- Doxapram Impurity 32 (CAS CATO-C4X-197332)
- Doxapram Impurity 33 (CAS CATO-C4X-197333)
- Doxapram (CAS 309-29-5)
- Doxapram Impurity 10 (CAS 3192-92-5)
- Doxapram Impurity 31 (CAS 1415394-56-7)
Recommended Standards
- 1G-323S 320420-86-8 [(3Z)-1-[(4-chlorophenyl)methyl]-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino 3-chloropropanoate (CAS 320420-86-8)
- 9- (Bromomethyl) - 2, 3, 6, 7- tetramethoxyphenanthrene (CAS 1150647-83-8)
- N-(3-chloro-4-methoxybenzyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 478259-45-9)
- 3-Amino-4-(4-bromophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one (CAS 1291488-44-2)
- Butylphthalide Impurity 71 (CAS 1379356-37-2)
- Aspirin Impurity 17 (CAS 77527-00-5)
- Pethidine Hydrochloride EP Impurity C (CAS CATO-C4X-22324)
- 2-(3,4-Dimethoxyphenyl)-N-(4-methylbenzyl)ethan-1-amine hydrobromide (CAS 1609408-85-6)
- 7-Chloro-1H-quinazoline-2,4-dione (CAS 13165-35-0)
- 4-(Cyclopropylmethoxy)picolinic acid (CAS 794515-63-2)
- N-((4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)-2-methylbenzamide (CAS 1091075-03-4)
- DPPF Pd G4 (CAS 1621274-17-6)
- (3-(4-Fluorophenyl)azepan-1-yl)(thiophen-2-yl)methanone (CAS 1797140-00-1)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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