Bumetanide Impurity 99 CAS CATO-C4X-198699

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-198699
Molecular FormulaC17H18N2O5S
Molecular Weight362.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bumetanide Impurity 99 CAS CATO-C4X-198699 chemical structure

Description

CATO supplies Bumetanide Impurity 99 (CAS CATO-C4X-198699), a pharmacopoeial impurity reference standard (molecular formula C17H18N2O5S, MW 362.40 g/mol) used for the identification and quantification of trace impurities in APIs.

Bumetanide Impurity 99 (C17H18N2O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Bumetanide Impurity 99 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H18N2O5S
Molecular Weight362.40 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2
Sulfur Atoms1

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