Nicotinamide impurity 20 CAS CATO-C4X-200020
| CAS No. | CATO-C4X-200020 |
| Molecular Formula | C7H8Cl2N2 |
| Molecular Weight | 191.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Nicotinamide impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Nicotinamide impurity 20 (CAS CATO-C4X-200020) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8Cl2N2 and a molecular weight of 191.06 g/mol.
Structurally, Nicotinamide impurity 20 (C7H8Cl2N2) contains a nitrile group, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 191.06 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H8Cl2N2 |
| Molecular Weight | 191.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Nicotinamide Standards
- Nicotinamide impurity 21 (CAS CATO-C4X-200021)
- Nicotinamide impurity 26 (CAS CATO-C4X-200026)
- Nicotinamide Impurity 11 (CAS 39642-60-9)
- Nicotinamide Impurity 9 (CAS 536-33-4)
- Nicotinamide impurity 24 (CAS CATO-C4X-200024)
- Nicotinamide Impurity 12 (CAS CATO-C4X-200012)
- Nicotinamide Impurity 8 (CAS 4314-66-3)
- Nicotinamide-d4 N-Oxide_x0000_ (d4 Major) (CAS 1246817-64-0)
Recommended Standards
- 3,6-Dichloro-4-Propylpyridazine (CAS 175215-06-2)
- Anagrelide Impurity 10 (CAS 147249-42-1)
- 4,6-Dichloro-N,N-dimethylpyridin-2-amine (CAS 849937-99-1)
- Opicapone impurity 66 (CAS 1639373-19-5)
- Hyoscyamine Impurity 4 (CAS CATO-C4X-34374)
- Relebactam Impurity 29 (CAS CATO-C4X-214429)
- Ciprofloxacin Impurity 19 (CAS 26832-89-3)
- Bromhexine Impurity 10 (CAS 2512203-87-9)
- 1-(4-Methylpyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 853318-49-7)
- Ivabradine Impurity 61 HCl (CAS 304465-03-0(Free Base))
- 2-(2-Phenyl-1H-indol-3-yl)ethanamine (CAS 1217-80-7)
- Tert-butyl (3-(1-fluoro-2-hydroxyethyl)azetidin-3-yl)carbamate (CAS 2306275-22-7)
- 1,3-Dichloro-4-difluoromethoxy-2-nitrobenzene (CAS 1803714-79-5)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com