Crisaborole Impurity 55 CAS CATO-C4X-202155
| CAS No. | CATO-C4X-202155 |
| Molecular Formula | C14H9BrO4 |
| Molecular Weight | 321.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Crisaborole Impurity 55 (CAS CATO-C4X-202155) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9BrO4 and a molecular weight of 321.12 g/mol.
Structurally, Crisaborole Impurity 55 (C14H9BrO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 321.12 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Crisaborole Impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9BrO4 |
| Molecular Weight | 321.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Crisaborole Standards
- Crisaborole Impurity 19 (CAS CATO-C4X-202119)
- Crisaborole impurity 121 (CAS CATO-C4X-2021121)
- Crisaborole Impurity 57 (CAS CATO-C4X-202157)
- Crisaborole impurity 118 (CAS CATO-C4X-2021118)
- Crisaborole Impurity 58 (CAS CATO-C4X-202158)
- Crisaborole impurity 127 (CAS CATO-C4X-2021127)
- Crisaborole lmpurity 95 (CAS CATO-C4X-202195)
- Crisaborole lmpurity 73 (CAS 2473730-47-9)
Recommended Standards
- 3-Iodo-1-(methylsulfonyl)-1h-indole (CAS 117637-81-7)
- Regadenoson Impurity 33 (CAS 13276-52-3)
- 2-Iodo-5,6-dimethoxybenzo[d]thiazole (CAS 1188079-16-4)
- Succinimidyl-4-(bromoacetamido)butanoate (CAS 95413-05-1)
- Perindopril EP Impurity D (CAS 130061-28-8)
- Cytarabine EP Impurity H (CAS 31698-14-3)
- Decitabine Impurity 45 (CAS CATO-C4X-113745)
- 3-Isopropyl-4H-1,2,4-triazol-4-amine (CAS 735212-04-1)
- 2-((2,3-Difluorophenoxy)methyl)-1,3-dioxolane (CAS 1443346-18-6)
- Chlorodifluoromethyl Phenyl Sulfone (CAS 930836-30-9)
- 5-Chloro-3-methoxy-2-nitropyridine (CAS 152684-28-1)
- 7-(3-Fluoro-4-methylphenyl)-2,5,6-trimethyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 950418-23-2)
- 7-Methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 700-52-7)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com