Osimertinib Impurity 22 CAS CATO-C4X-204522
| CAS No. | CATO-C4X-204522 |
| Molecular Formula | C56H66N14O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Osimertinib Impurity 22 (C56H66N14O4HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 30.0, corresponding to approximately 30 ring(s) or double-bond equivalent(s). With a molecular weight of 1035.70 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Osimertinib Impurity 22 (CAS CATO-C4X-204522) is a certified pharmaceutical impurity reference standard with the molecular formula C56H66N14O4HCl and a molecular weight of 1035.70 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Osimertinib Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C56H66N14O4 4*HCl |
| Molecular Weight | 1035.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 14 |
Related Osimertinib Standards
- Osimertinib Impurity 5 (CAS 1009298-59-2)
- Osimertinib Impurity 8 (CAS 1421372-66-8)
- Osimertinib Impurity N1 (CAS 1421372-67-9)
- Osimertinib Impurity N2 (CAS 1421373-36-5 (free base))
- Osimertinib (CAS 1421373-65-0)
- Osimertinib Impurity 10 (CAS 1421373-98-9)
- Osimertinib Impurity N3 (CAS 1421373-99-0)
- Osimertinib-3 (CAS 1446700-26-0)
Recommended Standards
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- 4-[ethyl(propyl)amino]benzoic acid hydrochloride (CAS 1221724-08-8)
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- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com