Ruxolitinib Impurity 101 CAS CATO-C4X-2058101

Purity 95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2058101
Molecular FormulaC9H13BrN2O
Molecular Weight245.12 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ruxolitinib Impurity 101 CAS CATO-C4X-2058101 chemical structure

Description

As a certified reference material (CRM), Ruxolitinib Impurity 101 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies Ruxolitinib Impurity 101 (CAS CATO-C4X-2058101), a pharmacopoeial impurity reference standard (molecular formula C9H13BrN2O, MW 245.12 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ruxolitinib Impurity 101 (C9H13BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC9H13BrN2O
Molecular Weight245.12 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentBr-containing
Nitrogen Atoms2

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