Ruxolitinib Impurity 14 CAS CATO-C4X-2058114
| CAS No. | CATO-C4X-2058114 |
| Molecular Formula | C11H14BrN3 |
| Molecular Weight | 268.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ruxolitinib Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ruxolitinib Impurity 14 (CAS CATO-C4X-2058114), a pharmacopoeial impurity reference standard (molecular formula C11H14BrN3, MW 268.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Ruxolitinib Impurity 14 (C11H14BrN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H14BrN3 |
| Molecular Weight | 268.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 13 (CAS CATO-C4X-2058113)
- Ruxolitinib Impurity 36 (CAS CATO-C4X-205836)
- Ruxolitinib Impurity 14 (CAS CATO-C4X-205814)
- Ruxolitinib Impurity 103 (CAS CATO-C4X-2058103)
- Ruxolitinib Impurity 229 (CAS CATO-C4X-2058229)
- Ruxolitinib Impurity 237 (CAS CATO-C4X-2058237)
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Ruxolitinib Impurity 118 (CAS CATO-C4X-2058118)
Recommended Standards
- 2,3-Dichloro-n-propylbenzenesulfonamide (CAS 1094563-52-6)
- (S)-3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile (CAS 2183286-19-1)
- 4,4,5,5-tetramethyl-2-(1,4-dioxaspiro[4.5]decan-8-yl)-1,3,2-dioxaborolane (CAS 1106871-37-7)
- (R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile (CAS 1146629-83-5)
- Montelukast Impurity 48 (CAS 87764-54-3)
- Ornidazole impurity 50 (CAS CATO-C4X-133150)
- Drospirenone EP Impurity I (CAS 2896199-04-3)
- Choline fenofibrate Impurity 23 (CAS 154356-97-5)
- 1-{4-[(4-carboxypiperidin-1-yl)sulfonyl]-2-nitrophenyl}piperidine-4-carboxylic acid (CAS 866132-63-0)
- 3-(4-(sec-Butyl)phenyl)-1H-pyrazole-5-carboxylic acid (CAS 1038539-54-6)
- 4-(4-Cyclohexylphenyl)-4-oxo-2-{[(thiophen-2-yl)methyl]amino}butanoic acid (CAS 329702-87-6)
- 2-(Ethylamino)-N-(4-morpholinophenyl)acetamide dihydrochloride (CAS 1170568-60-1)
- 2-Amino-5-(difluoromethyl)-6-iodonicotinonitrile (CAS 1803698-86-3)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com