Clofazimine Impurity 10 CAS CATO-C4X-207110
| CAS No. | CATO-C4X-207110 |
| Molecular Formula | C12H9ClN2O2 |
| Molecular Weight | 248.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Clofazimine Impurity 10 (CAS CATO-C4X-207110) is a certified pharmaceutical impurity reference standard with the molecular formula C12H9ClN2O2 and a molecular weight of 248.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Clofazimine Impurity 10 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 248.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O2 |
| Molecular Weight | 248.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ＞95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clofazimine Standards
- Clofazimine Impurity 11 (CAS 74002-27-0)
- Clofazimine Impurity 5 (CAS 23008-56-2)
- Clofazimine Impurity 19 (CAS CATO-C4X-207119)
- Clofazimine Impurity 15 (CAS CATO-C4X-207115)
- Clofazimine Impurity 16 (CAS CATO-C4X-207116)
- Clofazimine Impurity 18 (CAS CATO-C4X-207118)
- Clofazimine Impurity 13 (CAS CATO-C4X-207113)
- Clofazimine Impurity 6 (CAS CATO-C4X-20716)
Recommended Standards
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- 1-(2-Chlorophenyl)-1h-1,2,4-triazol-5-amine (CAS 1247575-06-9)
- 5-((Methylthio)methyl)-1,3,4-thiadiazol-2-amine (CAS 383130-36-7)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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