Vincristine Impurity 21 CAS CATO-C4X-208921
| CAS No. | CATO-C4X-208921 |
| Molecular Formula | C46H54N4O11 |
| Molecular Weight | 838.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Vincristine Impurity 21 (C46H54N4O11) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Vincristine Impurity 21 (CAS CATO-C4X-208921, C46H54N4O11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vincristine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C46H54N4O11 |
| Molecular Weight | 838.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Vincristine Standards
- Vincristine Impurity N1 (CAS 947527-73-3)
- Vincristine EP Impurity A (CAS CATO-C4X-20891)
- Vincristine Impurity 15 (CAS CATO-C4X-208915)
- Vincristine Impurity 20 (CAS CATO-C4X-208920)
- Vincristine Impurity 19 (CAS CATO-C4X-208919)
- Vincristine Impurity 18 (CAS CATO-C4X-208918)
- Vincristine EP Impurity G (CAS CATO-C4X-20897)
- Vincristine EP Impurity H (CAS 865-21-4)
Recommended Standards
- Rifampicin Impurity 9 (CAS CATO-C4X-14569)
- 2-Methoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy) carbonyl]oxy]ethyl ester (Candesartan Cilexetil Impurit) (CAS 1246818-56-3)
- Rifampicin EP Impurity B (CAS 125833-03-6)
- N-Trityl Candesartan Cilexetil Methoxy Analogue (CAS 1797867-82-3)
- Phloroglucinol Impurity 67 (CAS CATO-C4X-221767)
- Momelotinib impurity 9 (CAS CATO-C4X-33779)
- Clonazepam impurity 16 (CAS CATO-C4X-140316)
- Des-Phg-Pasireotide (CAS CATO-C4X-20083)
- N-(4-(tert-Butyl)phenyl)-2-(isopropyl((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)amino)acetamide (CAS 1197972-50-1)
- (3-Methylindolin-3-yl)methanol (CAS 1067891-36-4)
- 2-[(2-Aminophenyl)thio]benzonitrile (CAS 140425-65-6)
- 1-(2,4-Dimethylphenyl)cyclopropan-1-amine (CAS 1314712-03-2)
- 1-CYCLOPENTYL-1H-PYRAZOL-4-AMINE HCL (CAS 1216126-64-5)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com