Estradiol Impurity 35 CAS 1373116-15-4
| CAS No. | 1373116-15-4 |
| Molecular Formula | C28H38O4 |
| Molecular Weight | 438.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Estradiol Impurity 35 (CAS 1373116-15-4) is a certified pharmaceutical impurity reference standard with the molecular formula C28H38O4 and a molecular weight of 438.60 g/mol.
Based on its molecular formula C28H38O4, Estradiol Impurity 35 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estradiol Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H38O4 |
| Molecular Weight | 438.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
Related Estradiol Standards
- Estradiol Valerate Impurity 20 (CAS CATO-C4X-284220)
- Estradiol Valerate EP Impurity E (CAS 63042-28-4)
- Estradiol Valerate EP Impurity H (CAS 1421283-56-8)
- β-Estradiol 3,17-DisulfateDISCONTINUED, offer E888945 (CAS 3233-70-3)
- β-Estradiol 3-benzoate 17-n-butyrate (CAS 63042-18-2)
- Estradiol Impurity 43 (CAS 19590-55-7)
- 17β-Estradiol 17β-D-Glucuronide (CAS 1806-98-0)
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Recommended Standards
- Cortistatin J (CAS 944804-62-0)
- Estrone Impurity 8 (CAS CATO-C4X-21058)
- A-NOR-5α-ANDROSTAN-2α, 17α-DIETHYNYL-2β, 17β-DIOL DIPROPIONATE (CAS 56470-64-5)
- (E)-N-Mesityl-4-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanamide (CAS 6605-21-6)
- Exemestane EP Impurity F (CAS 72648-46-5)
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- Arotinolol Impurity 77 (CAS CATO-C4X-185477)
- 1,1-Dimethylbutyl 2-methyl-2-propenoate (CAS 100472-88-6)
- 5-Cyclopropyl-5-methylimidazolidine-2,4-dione (CAS 5470-46-2)
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- Methyl 2-(4'-Hydroxybenzoyl)benzoate (CAS 21147-23-9)
- 1-Azetidin-1-yl-ethanone (CAS 45467-31-0)
- tert-Butyl 2-(hydroxymethyl)-4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carboxylate (CAS 165947-56-8)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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