Gadobutrol impurity 176 CAS CATO-C4X-2120176
| CAS No. | CATO-C4X-2120176 |
| Molecular Formula | C20H38N4O9 |
| Molecular Weight | 478.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Gadobutrol impurity 176 (CAS CATO-C4X-2120176) is a certified pharmaceutical impurity reference standard with the molecular formula C20H38N4O9 and a molecular weight of 478.54 g/mol.
The molecular framework of Gadobutrol impurity 176 (C20H38N4O9) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H38N4O9 |
| Molecular Weight | 478.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol impurity 175 (CAS CATO-C4X-2120175)
- Gadobutrol Impurity 79 (CAS 105855-71-8)
- Gadobutrol Impurity 16 (CAS CATO-C4X-212016)
- Gadobutrol Impurity 119 (CAS CATO-C4X-2120119)
- Gadobutrol Impurity 142 (CAS CATO-C4X-2120142)
- Gadobutrol Impurity 144 (CAS CATO-C4X-2120144)
- Gadobutrol impurity 177 (CAS CATO-C4X-2120177)
- Gadobutrol Impurity 136 (CAS CATO-C4X-2120136)
Recommended Standards
- Finerenone Impurity 82 (CAS CATO-C4X-288082)
- Selexipag Impurity 39 (CAS CATO-C4X-196139)
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- Ivabradine Impurity 18 (CAS 2458312-06-4)
- Tiotropium Impurity 29 (CAS 213967-57-8)
- Lorazepam EP Impurity D (CAS 54699-91-1)
- Fluorouracil Impurity 11 (Mixture of Diastereomers) (CAS 37103-91-6)
- Di-n-butylbis(1-thioglycerol)tin (CAS 68298-38-4)
- (6-Chloro-4-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1360958-10-6)
- 4-((6-Chloropyridin-3-yl)methoxy)benzonitrile (CAS 861207-55-8)
- 7-Amino-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one (CAS 1190319-39-1)
- 1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]piperazine (CAS 222544-69-6)
- 2-Methyl-3-oxo-1,2,3,4-tetrahydroisoquinoline-5-carbonitrile (CAS 1547297-66-4)
- Peptide Impurity 15 (CAS 1227750-69-7)
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