Degarelix Impurity 6 CAS CATO-C4X-21366
| CAS No. | CATO-C4X-21366 |
| Molecular Formula | C74H91ClN16O14 |
| Molecular Weight | 1464.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Degarelix Impurity 6 (CAS CATO-C4X-21366, C74H91ClN16O14) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Degarelix Impurity 6 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1464.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C74H91ClN16O14 |
| Molecular Weight | 1464.07 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 37.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 16 |
Related Degarelix Standards
- Degarelix Impurity 3 (CAS 2648486-37-5)
- Degarelix Impurity 4 (CAS CATO-C4X-21364)
- Degarelix Impurity 5 (CAS CATO-C4X-21365)
- Degarelix Impurity 7 (CAS CATO-C4X-21367)
- Degarelix-d7 (CAS 214766-78-6（unlabelled）)
- Degarelix Impurity 8 (CAS 2648486-38-6)
- Degarelix Acetate (CAS 934016-19-0)
- Degarelix Acetate Hydrate (CAS 934246-14-7)
Recommended Standards
- [6-[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]-2,4-dioxo-pyrimidin-5-yl]prop-2-enoylamino]hexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxo-spiro[isobenzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate (CAS 1194507-30-6)
- Ethanamine, 2-[[2,4,8,10-tetrakis(1,1-dimethylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-yl]oxy]-N,N-bis[2-[[2,4,8,10-tetrakis(1,1-dimethylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-yl]oxy]ethyl]- (CAS 80410-33-9)
- Venetoclax Impurity 28 (CAS 2573767-93-6)
- LICA 38 (CAS 103432-54-8)
- Ciprofloxacin 7-Chloro-6-Desethylene Impurity (CAS 528851-30-1)
- Daprodustat impurity 27 (CAS 960540-96-9)
- Nerandomilast impurity 20 (CAS CATO-C4X-347320)
- {[3,5-bis(trifluoromethyl)phenyl]imino}[tris(3-methylphenyl)]phosphorane (CAS 260368-14-7)
- 3-Cyano-1H-1,2,4-triazole-1-acetic Acid (CAS 1247628-40-5)
- 2-(Difluoromethyl)-6-hydroxy-5-(trifluoromethyl)pyridine-3-carboxylic acid (CAS 1805498-62-7)
- 4-(6-Bromopyrimidin-4-yl)morpholine (CAS 1017781-95-1)
- {[5-(3-methylphenyl)thiophen-2-yl]methyl}(propan-2-yl)amine hydrochloride (CAS 1221724-39-5)
- 3-(Cyclopentylformamido)propanoic acid (CAS 923225-18-7)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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