Rosiglitazone Impurity 4 CAS CATO-C4X-21794
| CAS No. | CATO-C4X-21794 |
| Molecular Formula | C18H23N3O2 |
| Molecular Weight | 313.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rosiglitazone Impurity 4.
CATO supplies Rosiglitazone Impurity 4 (CAS CATO-C4X-21794), a pharmacopoeial impurity reference standard (molecular formula C18H23N3O2, MW 313.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rosiglitazone Impurity 4 (C18H23N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rosiglitazone Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23N3O2 |
| Molecular Weight | 313.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Rosiglitazone Standards
- Rosiglitazone Impurity 6 (CAS CATO-C4X-21796)
- Rosiglitazone Impurity 2 (CAS 1797979-55-5)
- Rosiglitazone Impurity (5-[4-N-(2-Pyridylamino)ethoxy]benzylidene] thiazolidine-2,4-dione) (CAS 643764-88-9)
- Rosiglitazone (CAS 122320-73-4)
- Rosiglitazone-d3 (CAS 1132641-22-5)
- Rosiglitazone Sodium (CAS 316371-83-2)
- Rosiglitazone Impurity 3 (CAS 2142519-15-9)
- Rosiglitazone N-(2-Succinic Acid) (CAS 956239-35-3)
Recommended Standards
- Dopamine Impurity 35 (CAS CATO-C4X-190835)
- Huperzine A Impurity 9 (CAS CATO-C4X-31239)
- Dopamine Impurity 33 (CAS CATO-C4X-190833)
- Nemonoxacin Impurity 100 (CAS CATO-C4X-3128100)
- Bilastine Impurity 40 (CAS 2199440-16-7)
- Lurasidone Impurity 71 (CAS CATO-C4X-102871)
- Tadalafil Impurity 141 (CAS 477970-21-1)
- 4-Chloropyridine<I>N</I>-oxide (CAS 1121-76-2)
- 2-((2-Fluorophenyl)amino)-5-methylthiazole-4-carboxylic acid (CAS 1391741-81-3)
- (E)-2-(2-Methylbut-2-enamido)acetic acid (CAS 35842-45-6)
- 2-((4-Amino-5-(4-methylphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 667879-44-9)
- 3,5-Dimethylimidazolidine-2,4-dione (CAS 6851-79-2)
- (1E)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}methanimine (CAS 297149-81-6)
- Exenatide (CAS 141758-74-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com