Berberine Impurity 1 CAS CATO-C4X-21991
| CAS No. | CATO-C4X-21991 |
| Molecular Formula | C19H16NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 357.79 g/mol gives Berberine Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Berberine Impurity 1 (CAS CATO-C4X-21991) is a certified pharmaceutical impurity reference standard with the molecular formula C19H16NO4Cl and a molecular weight of 357.79 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Berberine Impurity 1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Berberine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16NO4 Cl |
| Molecular Weight | 357.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Berberine Standards
- Berberine Impurity 33 (CAS 100101-07-3)
- Berberine Impurity 15 Chloride (CAS 1186107-72-1)
- Berberine Chloride hydrate (CAS 141433-60-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- Berberine Impurity 14 (CAS 2043361-62-0)
- Berberine (CAS 2086-83-1)
- Berberine Impurity 16 Chloride (CAS 2363741-22-2)
- Berberine Impurity 29 (CAS 2375597-30-9)
Recommended Standards
- Baxdrostat Impurity 34 (CAS 3024295-81-3)
- Linezolid Impurity 96 (CAS 152139-76-9)
- Carfilzomib Impurity 45 (CAS 1660143-42-9)
- 6,7-Dihydrothieno[3,2-c]pyridine-5(4h)-carbothioamide (CAS 953900-64-6)
- (1S,3R,4R)-2-tert-Butyl 3-ethyl 2-azabicyclo[2.2.1]heptane-2,3-dicarboxylate (CAS 228868-56-2)
- DL-alpha-O-Benzylglycerol (CAS 13071-59-5)
- Ozanimod Impurity 24 (CAS CATO-C4X-290224)
- 3-Cyclopropoxy-2-ethyl-N-methylisonicotinamide (CAS 1243290-16-5)
- (2-Carbamoylpyridin-4-yl)boronic acid (CAS 1443112-29-5)
- Peptide Impurity 05 (CAS 2322924-83-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com