Berberine Impurity 10 CAS CATO-C4X-219910
| CAS No. | CATO-C4X-219910 |
| Molecular Formula | C20H18NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Berberine Impurity 10 (CAS CATO-C4X-219910), a pharmacopoeial impurity reference standard (molecular formula C20H18NO4Cl, MW 371.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Berberine Impurity 10 (C20H18NO4Cl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 371.82 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Berberine Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18NO4 Cl |
| Molecular Weight | 371.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Berberine Standards
- Berberine Impurity 33 (CAS 100101-07-3)
- Berberine Impurity 15 Chloride (CAS 1186107-72-1)
- Berberine Chloride hydrate (CAS 141433-60-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- Berberine Impurity 14 (CAS 2043361-62-0)
- Berberine (CAS 2086-83-1)
- Berberine Impurity 16 Chloride (CAS 2363741-22-2)
- Berberine Impurity 29 (CAS 2375597-30-9)
Recommended Standards
- Dalilesen Impurity 60 (CAS CATO-C4X-301060)
- Flurbiprofen Impurity 107 (CAS CATO-C4X-1444107)
- Ropivacaine impurity 29 (CAS CATO-C4X-175329)
- (E)-3-[3-(2-Pyrimidinyloxy)phenyl]-2-(2-thienyl)-2-propenenitrile (CAS 861210-11-9)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 329079-95-0)
- 3-Ethyl-1,2-dimethyl-1H-imidazol-3-ium 4-methylbenzenesulfonate (CAS 783321-71-1)
- Bimatoprost Impurity 16 (CAS 144358-71-4)
- Bilastine Impurity 138 (CAS CATO-C4X-2253138)
- 2-{8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6-tetraen-4-yloxy}acetic acid (CAS 34855-08-8)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com