Avatrombopag Impurity 106 CAS CATO-C4X-2234106
| CAS No. | CATO-C4X-2234106 |
| Molecular Formula | C17H22BrClN4OS |
| Molecular Weight | 445.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Avatrombopag Impurity 106 (CAS CATO-C4X-2234106) is a certified pharmaceutical impurity reference standard with the molecular formula C17H22BrClN4OS and a molecular weight of 445.80 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution, Avatrombopag Impurity 106 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H22BrClN4OS |
| Molecular Weight | 445.80 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Avatrombopag Standards
- Avatrombopag Impurity 79 (CAS CATO-C4X-223479)
- Avatrombopag Impurity 98 (CAS CATO-C4X-223498)
- Avatrombopag Impurity 13 (CAS CATO-C4X-223413)
- Avatrombopag Impurity 64 (CAS CATO-C4X-223464)
- Avatrombopag Impurity 10 (CAS CATO-C4X-223410)
- Avatrombopag Impurity 78 (CAS CATO-C4X-223478)
- Avatrombopag Impurity 75 (CAS CATO-C4X-223475)
- Avatrombopag Impurity 97 (CAS CATO-C4X-223497)
Recommended Standards
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