Avatrombopag Impurity 64 CAS CATO-C4X-223464
| CAS No. | CATO-C4X-223464 |
| Molecular Formula | C14H8Cl2N4S4 |
| Molecular Weight | 431.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Avatrombopag Impurity 64 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Avatrombopag Impurity 64 (CAS CATO-C4X-223464), a pharmacopoeial impurity reference standard (molecular formula C14H8Cl2N4S4, MW 431.41 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Avatrombopag Impurity 64 (C14H8Cl2N4S4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2N4S4 |
| Molecular Weight | 431.41 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 4 |
Related Avatrombopag Standards
- Avatrombopag Impurity 13 (CAS CATO-C4X-223413)
- Avatrombopag Impurity 98 (CAS CATO-C4X-223498)
- Avatrombopag Impurity 77 (CAS CATO-C4X-223477)
- Avatrombopag Impurity 34 (CAS CATO-C4X-223434)
- Avatrombopag Impurity 44 (CAS 570407-63-5)
- Avatrombopag Impurity 106 (CAS CATO-C4X-2234106)
- Avatrombopag Impurity 79 (CAS CATO-C4X-223479)
- Avatrombopag Impurity 10 (CAS CATO-C4X-223410)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com