Avatrombopag Impurity 105 CAS CATO-C4X-2234105
| CAS No. | CATO-C4X-2234105 |
| Molecular Formula | C23H23Cl2N7O4S2 |
| Molecular Weight | 596.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Avatrombopag Impurity 105 (CAS CATO-C4X-2234105), a pharmacopoeial impurity reference standard (molecular formula C23H23Cl2N7O4S2, MW 596.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Avatrombopag Impurity 105 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 596.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H23Cl2N7O4S2 |
| Molecular Weight | 596.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 94 (CAS CATO-C4X-223494)
- Avatrombopag Impurity 137 (CAS CATO-C4X-2234137)
- Avatrombopag Impurity 57 (CAS CATO-C4X-223457)
- Avatrombopag Impurity 22 (CAS CATO-C4X-223422)
- Avatrombopag Impurity 7 (CAS CATO-C4X-22347)
- Avatrombopag Impurity 1 (CAS 2626934-45-8)
- Avatrombopag impurity 133 (CAS CATO-C4X-2234133)
- Avatrombopag Impurity 101 (CAS CATO-C4X-2234101)
Recommended Standards
- Quercetin 3-sambubioside (CAS 83048-35-5)
- Mistletoe neoglucoside III (CAS 118985-27-6)
- BIs[2-(sulphosuccinimidooxycarbonyloxy)ethyl]sulphone (CAS 161011-72-9)
- Octahydronaphthalene-1,5-dione (CAS 13913-82-1)
- Lacidipine impurity 9 (CAS CATO-C4X-16719)
- Imrecoxib Impurity 59 (CAS CATO-C4X-237959)
- Cefotaxime Impurity 73 (CAS CATO-C4X-120173)
- Methyl Propionate (CAS 554-12-1)
- 4-Hydroxy-6-methoxyquinoline-3-carboxylic acid (CAS 28027-16-9)
- tert-Butyl 2-(1H-indol-3-yl)piperazine-1-carboxylate (CAS 886771-62-6)
- Sunitinib Impurity 70 (CAS CATO-C4X-133370)
- 1-(Isobutylsulfinyl)-2-methylpropane (CAS 3085-40-3)
- 2-(2-Formyl-1H-pyrrol-1-yl)-2-phenylacetic acid (CAS 910443-20-8)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com