Avatrombopag Impurity 13 CAS CATO-C4X-223413

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-223413
Molecular FormulaC14H8Cl2N4S4
Molecular Weight431.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avatrombopag Impurity 13 CAS CATO-C4X-223413 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 431.41 g/mol gives Avatrombopag Impurity 13 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Avatrombopag Impurity 13 (CAS CATO-C4X-223413, C14H8Cl2N4S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Avatrombopag Impurity 13 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 431.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Avatrombopag Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H8Cl2N4S4
Molecular Weight431.41 g/mol
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms4
Sulfur Atoms4

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