Avatrombopag Impurity 15 CAS CATO-C4X-223415
| CAS No. | CATO-C4X-223415 |
| Molecular Formula | C16H21Cl2N3O |
| Molecular Weight | 342.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Avatrombopag Impurity 15 (CAS CATO-C4X-223415), a pharmacopoeial impurity reference standard (molecular formula C16H21Cl2N3O, MW 342.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Avatrombopag Impurity 15 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 342.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Avatrombopag Impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21Cl2N3O |
| Molecular Weight | 342.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Avatrombopag Standards
- Avatrombopag Impurity 11 (CAS CATO-C4X-223411)
- Avatrombopag Impurity 76 (CAS CATO-C4X-223476)
- Avatrombopag Impurity 42 (CAS CATO-C4X-223442)
- Avatrombopag Impurity 49 (CAS CATO-C4X-223449)
- Avatrombopag Impurity 107 (CAS CATO-C4X-2234107)
- Avatrombopag Impurity 116 (CAS CATO-C4X-2234116)
- Avatrombopag Impurity 4 (CAS 931395-73-2)
- Avatrombopag Impurity 74 (CAS CATO-C4X-223474)
Recommended Standards
- Brexpiprazole Impurity 37 (CAS CATO-C4X-113137)
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- Brexpiprazole Impurity 22 (CAS 2060027-95-2)
- 2-(3-(Trifluoromethyl)phenyl)hexahydro-1H-pyrrolo[3',4':4,5]isoxazolo[3,2-c][1,4]oxazine-1,3(2H)-dione (CAS 1212136-07-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com