Avatrombopag Impurity 4 CAS 931395-73-2
| CAS No. | 931395-73-2 |
| Molecular Formula | C14H17ClN2O4 |
| Molecular Weight | 312.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avatrombopag Impurity 4.
Avatrombopag Impurity 4 (CAS 931395-73-2) is a certified pharmaceutical impurity reference standard with the molecular formula C14H17ClN2O4 and a molecular weight of 312.75 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Avatrombopag Impurity 4 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17ClN2O4 |
| Molecular Weight | 312.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 74 (CAS CATO-C4X-223474)
- Avatrombopag Impurity 50 (CAS CATO-C4X-223450)
- Avatrombopag Impurity 72 (CAS CATO-C4X-223472)
- Avatrombopag Impurity 116 (CAS CATO-C4X-2234116)
- Avatrombopag impurity 125 (CAS CATO-C4X-2234125)
- Avatrombopag Impurity 49 (CAS CATO-C4X-223449)
- Avatrombopag impurity 134 (CAS CATO-C4X-2234134)
- Avatrombopag Impurity 24 (CAS 1534575-19-3)
Recommended Standards
- Estazolam Impurity 5 (CAS CATO-C4X-19225)
- Erlotinib Impurity 13 (CAS 183322-18-1)
- 1,1'-(2-Chloropropane-1,3-diyl)bis(1H-benzo[d][1,2,3]triazole) (CAS 187095-23-4)
- 318238-06-1 KS-00001VO7 methyl 5-(4-chlorophenyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 318238-06-1)
- Pentoxifylline Impurity 14 (CAS 16015-11-5)
- Alverine Impurity 13 HCl (CAS 61930-96-9(free base))
- Procaine Impurity 3 (CAS 619-19-2)
- Ethyl 3-(dimethyl-1,3-thiazol-5-yl)-3-oxopropanoate (CAS 1410695-10-1)
- 3-Hydroxy-7,8,3'-trimethoxyflavone (CAS 1017060-12-6)
- 9-Methyl-1,11-dihydro-2H-pyrimido[4,5-a]carbazol-2-one (CAS 248246-45-9)
- Ethyl 2,2-dimethylchroman-6-carboxylate (CAS 6630-24-6)
- 2-Cyclohexyl-1-methylquinazolin-4(1H)-one (CAS 60888-87-1)
- tert-Butyl (5-(tert-Butyl)isoxazol-3-yl)carbamate (CAS 89661-71-2)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com